the effect serum vitamin d normalization in preventing recurrences of benign paroxysmal positional vertigo .a case-control study
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abstract
background: benign paroxysmal positional vertigo (bppv) is a condition with recurrent attacks in a significant proportion of patients. the present case- control study was conducted to assess the influence of serum vitamin d normalization on recurrent attacks of vitamin d deficient patients. methods: diagnosis of bppv was made based on history and clinical examination and exclusion of other conditions. serum 25-hydroxy vitamin d (25-ohd) was measured using elisa method and a levels of < 20 ng/ml was considered a deficiency of vitamin d. inclusion criteria were as follows: history of recurrent attacks and serum 25-ohd<20.ng/ml. while the patients with history of trauma, surgery and chronic systemic diseases were excluded. the patients were classified into two groups: treatment and control, intermittently. both groups received epley rehabilitation therapy one session per week for 4 weeks but the treatment group received an additional supplement of 50.000 iu of vitamin d (cholecalciferol) weekly for two months to achieve serum 25-ohd ≥ 30 ng/ml and the study patients were followed-up for 6 months. results: twenty-seven patients were allocated to each group. at baseline, serum 25-ohd was similar (10.7±2.3 vs 11.41±1.9, p=0.23). at month 2, serum 25-ohd in the treatment group increased significantly to ≥ 30 ng/ ml, whereas serum 25-ohd in the control group remained unchanged (34.2±3.3 vs 10.6 10.6±2.2 ng/ml, p=0.001). during the follow-up period, attacks of bppv in the treatment group decreased significantly compared with the control group (14.8% vs 96.3% or= 0.18, p=0.001). conclusion: the findings of this study indicate that the normalization of serum vitamin d significantly reduces bppv recurrences.
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The effect serum vitamin D normalization in preventing recurrences of benign paroxysmal positional vertigo .a case-control study
Background: Benign paroxysmal positional vertigo (BPPV) is a condition with recurrent attacks in a significant proportion of patients. The present case- control study was conducted to assess the influence of serum vitamin D normalization on recurrent attacks of vitamin D deficient patients. Methods: Diagnosis of BPPV was made based on history and clinical examination and exclusion of other c...
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Journal title:
caspian journal of internal medicineجلد ۷، شماره ۳، صفحات ۱۷۳-۱۷۷
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